Bladder cancer-related BC10 (IPR009598)

Short name: BC10

Overlapping homologous superfamilies


Family relationships



This family consists of a series of short proteins of around 90 residues in length. The human protein O60629 (or BC10) has been implicated in bladder cancer where the transcription of the gene coding for this protein is nearly completely abolished in highly invasive transitional cell carcinomas (TCCs) [PMID: 15797904]. The protein is a small globular protein containing two transmembrane helices, and it is a multiply edited transcript. All the editing sites are found in either the 5'-UTR or the N-terminal section of the protein, which is predicted to be outside the membrane. The three coding edits are all non-synonymous and predicted to encode exposed residues [PMID: 11920613]. The function of this family is unknown.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.