Protein wntless (IPR009551)

Short name: Wntless

Overlapping homologous superfamilies


Family relationships



Protein wntless (Wls) regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism [PMID: 16678095, PMID: 16678096, PMID: 17108000]. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. It also plays also an important role in establishment of the anterior-posterior body axis formation during development [PMID: 19841259].

GO terms

Biological Process

GO:0016055 Wnt signaling pathway

Molecular Function

GO:0017147 Wnt-protein binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.