Family

Moricin family (IPR009456)

Short name: Moricin_fam

Overlapping homologous superfamilies

Family relationships

None.

Description

Moricin is a antibacterial peptide that is highly basic. The structure of moricin reveals that it is comprised of a long alpha-helix. The N terminus of the helix is amphipathic, and the C terminus of the helix is predominately hydrophobic. The amphipathic N-terminal segment of the alpha- helix is mainly responsible for the increase in permeability of the bacterial membrane which kills the bacteria [PMID: 11997013].

GO terms

Biological Process

GO:0042742 defense response to bacterium

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
ProDom