Family

Phosphatidylinositol N-acetylglucosaminyltransferase subunit C (IPR009450)

Short name: Plno_GlcNAc_GPI2

Family relationships

None.

Description

This entry represents the subunit C of the phosphatidylinositol N-acetylglucosaminyltransferase (PIG-C) and its yeast homologue, Gpi2. It catalyses the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. This step involves products of three or four genes in both yeast (GPI1, GPI2 and GPI3) and mammals (GPI1, PIG A, PIG H and PIG C), respectively [PMID: 8806613].

GO terms

Biological Process

GO:0006506 GPI anchor biosynthetic process

Molecular Function

GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF
Pfam
PANTHER