Family

Biogenesis of lysosome-related organelles complex 1 subunit 1 (IPR009395)

Short name: BLOC1S1

Family relationships

None.

Description

GCN5L1 (general control of amino acid synthesis 5-like 1), also known as BLOC1S1 (biogenesis of lysosome-related organelles complex 1 subunit 1). It is a component of the BLOC-1 complex, a complex required for normal biogenesis of lysosome-related organelles [PMID: 17182842]. GCN5L1 has been identified as a critical component of the mitochondrial protein acetylation programme [PMID: 22309213, PMID: 25400169]. It acts as a nutrient-sensing regulator that controls mitochondrial content through coordinated regulation of mitochondrial biogenesis and autophagy [PMID: 24356961].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0031083 BLOC-1 complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam