Family

23S rRNA methylase leader peptide (IPR009391)

Short name: ErmC

Family relationships

None.

Description

This family consists of several very short bacterial 23S rRNA methylase leader peptide (ErmC) sequences. ermC confers resistance to macrolide-lincosamide streptogramin B antibiotics by specifying a ribosomal RNA methylase, which results in decreased ribosomal affinity for these antibiotics. ermC expression is induced by exposure to erythromycin [PMID: 4018035].

GO terms

Biological Process

GO:0046677 response to antibiotic

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
ProDom