Family

NF-kappa-B-activating protein (IPR009269)

Short name: NKAP

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

The UPF0396 family includes NF-kappa-B-activating protein (Nkap). Nkap functions as a transcriptional repressor on Notch target genes, and is required for T cell development and acquisition of functional competency [PMID: 19409814, PMID: 21624937, PMID: 23481390].

GO terms

Biological Process

GO:0007219 Notch signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated

Molecular Function

GO:0003682 chromatin binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER