Domain

EB-1 binding (IPR009232)

Short name: EB1-bd

Domain relationships

None.

Description

This region at the C terminus of the APC proteins binds the microtubule-associating protein EB-1 [PMID: 11514192]. At the C terminus of the alignment is also a PDZ-binding domain. A short motif in the middle of the region appears to be found in the APC2 proteins (e.g. O95996).

GO terms

Biological Process

GO:0016055 Wnt signaling pathway

Molecular Function

GO:0008013 beta-catenin binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam