Domain

Killer toxin KP6, alpha subunit (IPR009096)

Short name: Killer_toxin_KP6_asu

Domain relationships

None.

Description

The killer toxin KP6 is secreted by Ustilago maydis (Smut fungus), a pathogen of Zea mays (Maize). KP6 is thought to disrupt intracellular potassium levels. KP6 toxin is encoded by a double-stranded RNA virus in the cell cytoplasm, which yields a pretoxin that is post-translationally cleaved into two polypeptide chains, alpha and beta, both of which are required for killer activity. The crystal structure of the alpha subunit revealed an alpha/beta sandwich with antiparallel beta-sheets [PMID: 10400668].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
GENE3D
SUPERFAMILY