Argininosuccinate lyase (IPR009049)

Short name: Argininosuccinate_lyase

Family relationships


Argininosuccinate lyase (ASL, EC: participates in arginine synthesis in all organisms catalysing the reversible breakdown of argininosuccinate to arginine and fumarate. The reaction is also part of the urea cycle [PMID: 15502303]. The crystal structures of ASLs from several species have been studied, in particular the duck delta1 and delta2 eye lens crystallins, which are inactive and active homologues of ASL, respectively [PMID: 11698398].

This entry represents argininosuccinate lyase and includes avian delta crystallins whose biological role is to provide the optically clear cellular protein of the eye lens.

GO terms

Biological Process

GO:0042450 arginine biosynthetic process via ornithine

Molecular Function

GO:0004056 argininosuccinate lyase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.