Domain

Moesin tail domain (IPR008954)

Short name: Moesin_tail

Domain relationships

None.

Description

The ezrin-radixin-moesin (ERM) protein family link actin filaments of cell surface structures to the plasma membrane, using a C-terminal F-actin binding segment and an N-terminal FERM domain, a common membrane binding module [PMID: 10847681]. ERM proteins are highly related members of the larger protein 4.1 superfamily. The sole Drosophila ERM protein, Moesin, functions in maintaining epithelial integrity by regulating cell-signalling events that affect actin organisation and polarity [PMID: 12511959].

This entry represents the actin-binding tail domain of ERM proteins.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003779 actin binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SUPERFAMILY