Family

Thyrotropin-releasing hormone (IPR008857)

Short name: TRH

Family relationships

None.

Description

This family consists of several thyrotropin-releasing hormone (TRH) proteins. Thyrotropin-Releasing Hormone (TRH) is a tripeptide (pGlu-His-Pro-NH2) hormone that is primarily produced in the paraventricular nucleus of the hypothalamus and represents the most proximal member of the hypothalamic-pituitary-thyroid (HPT) axis. It plays an important role in maintaining the thyroid hormone (TH) homeostasis [PMID: 19179434].

GO terms

Biological Process

GO:0009755 hormone-mediated signaling pathway

Molecular Function

GO:0008437 thyrotropin-releasing hormone activity

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF
PANTHER
Pfam