Semenogelin (IPR008836)

Short name: Semenogelin

Overlapping homologous superfamilies


Family relationships



This family consists of several mammalian secreted seminal proteins including semenogelin I and II. Freshly ejaculated Homo sapiens semen has the appearance of a loose gel in which the predominant structural protein components are the seminal vesicle secreted semenogelins (Sg) [PMID: 1584792]. This family also includes seminal vesicle secretory protein 3A from mouse, which has been shown to be involved in the coagulation of semen resulting in the formation of the copulatory plug [PMID: 11723121].

GO terms

Biological Process

GO:0050817 coagulation
GO:1901318 negative regulation of flagellated sperm motility

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.