Family

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 (IPR008814)

Short name: Swp1

Family relationships

None.

Description

Swp1 is an essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyses the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains [PMID: 8175708]. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity [PMID: 15831493].

GO terms

Biological Process

GO:0006487 protein N-linked glycosylation

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016021 integral component of membrane
GO:0008250 oligosaccharyltransferase complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER