Family

Phosphorylase kinase alpha/beta subunit (IPR008734)

Short name: PHK_A/B_su

Family relationships

Description

This family consists of several eukaryotic phosphorylase kinase alpha and beta subunits. Phosphorylase kinase (PHK) is a regulatory enzyme in glycogen metabolism. Mutations in the gene encoding the alpha subunit of PHK (PHKA2) have been shown to be responsible for X-linked liver glycogenosis (XLG). XLG, a frequent type of glycogen storage disease, is characterised by hepatomegaly and growth retardation [PMID: 9384616, PMID: 9835437].

GO terms

Biological Process

GO:0005977 glycogen metabolic process

Molecular Function

GO:0005516 calmodulin binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER