Family

Noggin (IPR008717)

Short name: Noggin

Family relationships

None.

Description

This family consists of the eukaryotic Noggin proteins. Noggin is a glycoprotein that binds bone morphogenetic proteins (BMPs) selectively and, when added to osteoblasts, it opposes the effects of BMPs. It has been found that noggin arrests the differentiation of stromal cells, preventing cellular maturation [PMID: 12633782].

GO terms

Biological Process

GO:0045596 negative regulation of cell differentiation

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF
PANTHER
Pfam