Family

Neurochondrin (IPR008709)

Short name: Neurochondrin

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This family contains several eukaryotic neurochondrin proteins. Neurochondrin induces hydroxyapatite resorptive activity in bone marrow cells resistant to bafilomycin A1, an inhibitor of macrophage- and osteoclast-mediated resorption. Expression of the gene is localised to chondrocyte, osteoblast, and osteocyte in the bone and to the hippocampus and Purkinje cell layer of cerebellum in the brain [PMID: 10231559].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER