Domain

LRV FeS4 cluster (IPR008665)

Short name: LRV_FeS

Domain relationships

None.

Description

This iron sulphur cluster is found at the N terminus of some proteins containing leucine-repeat variant (LRV) repeats (IPR004830). These proteins have a two-domain structure, composed of a small N-terminal domain containing a cluster of four Cys residues that houses the 4Fe:4S cluster, and a larger C-terminal domain containing the LRV repeats [PMID: 8946850]. Biochemical studies revealed that the 4Fe:4S cluster is sensitive to oxygen, but does not appear to have reversible redox activity.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam