Family

Lamina-associated polypeptide 1C (IPR008662)

Short name: Lamina-ass_polypeptide_CLAP1C

Family relationships

None.

Description

This entry contains Rattus norvegicus LAP1C proteins and several uncharacterised highly related sequences from both Mus sp. and humans. Lamina-associated polypeptide 1s (LAP1s), also known as Torsin-1A-interacting protein 1, are type 2 integral membrane proteins with a single membrane-spanning region of the inner nuclear membrane [PMID: 12061773]. LAP1s bind to both A- and B-type lamins and have a putative role in the membrane attachment and assembly of the nuclear lamina [PMID: 7721789].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam