Domain

PPPDE putative peptidase domain (IPR008580)

Short name: PPPDE_dom

Domain relationships

None.

Description

The PPPDE superfamily (after Permuted Papain fold Peptidases of DsRNA viruses and Eukaryotes), consists of predicted thiol peptidases with a circularly permuted papain-like fold. The inference of the likely DUB function of the PPPDE superfamily proteins is based on the fusions of the catalytic domain to Ub-binding PUG (PUB)/UBA domains and a novel alpha-helical Ub-associated domain (the PUL domain, after PLAP, Ufd3p and Lub1p) [PMID: 15483401].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
SMART
Pfam