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Overview
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Pathways & interactions
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Structures
Chondroitin N-acetylgalactosaminyltransferase (IPR008428)
Short name: Chond_GalNAc
Overlapping homologous superfamilies
None.
Family relationships
None.
Description
This family represents Chondroitin N-acetylgalactosaminyltransferase. Proteins have a type II transmembrane topology. The enzyme is involved in the biosynthetic initiation and elongation of chondroitin sulphate and is the key enzyme responsible for the selective chain assembly of chondroitin/dermatan sulphate on the linkage region tetrasaccharide common to various proteoglycans containing chondroitin/dermatan sulphate or heparin/heparan sulphate chains [PMID: 11788602, PMID: 11514575].
GO terms
Biological Process
No terms assigned in this category.
Molecular Function
GO:0008376 acetylgalactosaminyltransferase activity
Cellular Component
GO:0032580 Golgi cisterna membrane
Contributing signatures
- PF05679 (CHGN)