Domain

Ferritin/DPS protein domain (IPR008331)

Short name: Ferritin_DPS_dom

Domain relationships

Description

Ferritin is one of the major non-haem iron storage proteins in animals, plants, and microorganisms [PMID: 15222465]. It consists of a mineral core of hydrated ferric oxide, and a multi-subunit protein shell that encloses the former and assures its solubility in an aqueous environment.

In animals the protein is mainly cytoplasmic and there are generally two or more genes that encode closely related subunits - in mammals there are two subunits which are known as H(eavy) and L(ight). In plants ferritin is found in the chloroplast [PMID: 2211706].

This entry represents the main structural domain of ferritin. The domain is also found in other ferritin-like proteins such as members of the DNA protection during starvation (DPS) family [PMID: 15365182] and bacterioferritins [PMID: 18946693].

GO terms

Biological Process

GO:0006879 cellular iron ion homeostasis

Molecular Function

GO:0008199 ferric iron binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam