Active Site

Lipase, GDSL, active site (IPR008265)

Short name: Lipase_GDSL_AS


A variety of lipolytic enzymes with serine as part of the active site have been identified [PMID: 7610479]. Protein sequences which contain this active site signature include; Aeromonas hydrophila lipase, Vibrio mimicus arylesterase, Vibrio parahaemolyticus thermolabile haemolysin, rabbit phospholipase (AdRab-B), and Brassica napus anther-specific proline-rich protein. A serine has been identified as part of the active site in the A. hydrophila, V. mimicus and Escherichia coli enzymes.

GO terms

Biological Process

GO:0006629 lipid metabolic process

Molecular Function

GO:0016298 lipase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns