Active Site

Glycoside hydrolase, family 16, active site (IPR008263)

Short name: GH16_AS


O-Glycosyl hydrolases (EC:3.2.1.) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [PMID: 7624375, PMID: 8535779]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.

Glycoside hydrolase family 16 GH16 comprises enzymes with a number of known activities; lichenase (EC:; xyloglucan xyloglucosyltransferase (EC:; agarase (EC:; kappa-carrageenase (EC:; endo-beta-1,3-glucanase (EC:; endo-beta-1,3-1,4-glucanase (EC:; endo-beta-galactosidase (EC: Two closely clustered and conserved glutamates, which are part of this signature, have been shown to be involved in the catalytic activity of Bacillus licheniformis.

GO terms

Biological Process

GO:0005975 carbohydrate metabolic process

Molecular Function

GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns