Family

Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase (IPR008205)

Short name: GGGP_HepGP_synthase

Overlapping homologous superfamilies

Family relationships

Description

This entry represents geranylgeranylglyceryl phosphate (GGGP) synthase and Heptaprenylglyceryl phosphate (HepGP) synthase.

GGGP synthase is a prenyltransferase that catalyses the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. This entry also matches putative glycerol-1-phosphate prenyltransferases that may catalyse the transfer of a prenyl moiety to sn-glycerol-1-phosphate (G1P) [PMID: 18558723].

HepGP synthase is a prenyltransferase that catalyses in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP) [PMID: 21761520].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD
TIGRFAMs
HAMAP
Pfam