Family

Phosphoribosyl-ATP pyrophosphohydrolase (IPR008179)

Short name: PRib-ATP_PPHydrolase

Family relationships

Description

Phosphoribosyl-ATP pyrophosphatase, EC:3.6.1.31 catalyses the second step in the histidine biosynthetic pathway:

5-phosphoribosyl-ATP + H2O = 5-phosphoribosyl-AMP + PPi

The Neurospora crassa enzyme also catalyzes the reactions of histidinol dehydrogenase (EC:1.1.1.23) and phosphoribosyl-AMP cyclohydrolase (EC:3.5.4.19).

GO terms

Biological Process

GO:0000105 histidine biosynthetic process

Molecular Function

GO:0004636 phosphoribosyl-ATP diphosphatase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
HAMAP
TIGRFAMs