Family

Pro-FMRFamide-related neuropeptide FF (IPR008065)

Short name: NPFF

Family relationships

None.

Description

Neuropeptide FF (together with neuropeptides AF and SF, which are derived from the same precursor) belongs to a family of neuropeptides containing an RF-amide motif at their C-termini [PMID: 11325803]. Neuropeptide FF is found at high concentrations in the posterior pituitary, spinal cord, hypothalamus and medulla, and is believed to be involved in pain modulation, opioid tolerance, cardiovascular regulation, memory and neuroendocrine regulation.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005184 neuropeptide hormone activity
GO:0005102 receptor binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF
PRINTS
PANTHER
Pfam