Family

Atracotoxin, delta (IPR008017)

Short name: Atracotoxin_delta

Family relationships

None.

Description

Delta atracotoxin produces potentially fatal neurotoxic symptoms in primates by slowing the inactivation of voltage-gated sodium channels [PMID: 9384567]. The structure of atracotoxin comprises a core beta region containing a triple-stranded a thumb-like extension protruding from the beta region and a C-terminal helix. The beta region contains a cystine knot motif, a feature seen in other neurotoxic polypeptides [PMID: 9384567].

GO terms

Biological Process

GO:0009405 pathogenesis

Molecular Function

GO:0019871 sodium channel inhibitor activity

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
ProDom
GENE3D
PROSITE patterns