Domain

GATA-type transcription activator, N-terminal (IPR008013)

Short name: GATA_N

Domain relationships

None.

Description

GATA transcription factors mediate cell differentiation in a diverse range of tissues. Mutations are often associated with certain congenital human disorders. The six classical vertebrate GATA proteins, GATA-1 to GATA-6, are highly homologous and have two tandem zinc fingers. The classical GATA transcription factors function as transcription activators. In lower metazoans GATA proteins carry a single canonical zinc finger. This entry represents the N-terminal domain of the family of GATA transcription activators.

GO terms

Biological Process

GO:0045893 positive regulation of transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding
GO:0008270 zinc ion binding

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam