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Overview
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Pathways & interactions
Rhamnose/fucose mutarotase (IPR008000)
Short name: Rham/fucose_mutarotase
Overlapping homologous superfamilies
- Dimeric alpha-beta barrel (IPR011008)
Family relationships
- Rhamnose/fucose mutarotase (IPR008000)
- L-rhamnose mutarotase (IPR013448)
Description
Mutarotases are enzymes which interconvert the alpha and beta stereoisomers of monosaccharides, enhancing the rate of their metabolism. Proteins in this entry are homologues of the rhamnose mutarotase YiiL (P32156) from Escherichia coli, and are often encoded in rhamnose utilisation operons. YiiL is an enzyme which interconverts the alpha and beta stereoisomers of the pyranose form of L-rhamnose [PMID: 15060078]. It is not required for growth on rhamnose, but allows cells to utilise this carbon source more efficiently [PMID: 15876375].The structure of YiiL is distinct from other mutarotases, forming an asymmetric dimer stabilised by an intermolecular beta-sheet, hydrophobic interactions and a salt bridge [PMID: 15876375].
Included in this family is the L-fucose mutarotase from Xanthomonas campestris XCC4070 [PMID: 17144652], but not other L-fucose mutarotases.
GO terms
Biological Process
No terms assigned in this category.
Molecular Function
GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives
Cellular Component
GO:0005737 cytoplasm
Contributing signatures
- PF05336 (rhaM)