Family

RNA polymerase I specific transcription initiation factor RRN3 (IPR007991)

Short name: RNA_pol_I_trans_ini_fac_RRN3

Family relationships

None.

Description

This family consists of several eukaryotic proteins which are homologous to the Saccharomyces cerevisiae RRN3 protein. RRN3 is one of the RRN genes specifically required for the transcription of rDNA by RNA polymerase I (Pol I) in the S. cerevisiae [PMID: 8670901] RNA polymerase I complex within the nucleolus. In mammalian cells, the phosphorylation state of Rrn3 regulates rDNA transcription by determining the steady-state concentration of the Rrn3 [PMID: 12015311].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER