Family

MICOS complex subunit MIC19/MIC25 (IPR007964)

Short name: MIC19/MIC25

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

MIC19 (also known as ChChd3) and MIC25 (also known as ChChd6) are components of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane [PMID: 21081504, PMID: 22228767]. MIC19 plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology [PMID: 21081504].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0061617 MICOS complex
GO:0005739 mitochondrion

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam