Oligosaccharyltransferase complex subunit (IPR007915)

Short name: TMEM258/Ost5

Overlapping homologous superfamilies


Family relationships


This entry includes Ost5 from budding yeasts and TMEM258 from animals. Ost5 is an essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains [PMID: 9878773].

TMEM258 is a component of the oligosaccharyltransferase (OST) complex controlling ER stress and intestinal inflammation [PMID: 27974209].

GO terms

Biological Process

GO:0006487 protein N-linked glycosylation

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0034998 oligosaccharyltransferase I complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.