UNC-50 (IPR007881)

Short name: UNC-50

Family relationships



This family contains several eukaryotic transmembrane proteins which are related to the Caenorhabditis elegans protein UNC-50 Q10045. A mammalian homologue, UNCL is a novel inner nuclear membrane protein that associates with RNA and is involved in the cell-surface expression of neuronal nicotinic receptors. UNCL plays a broader role because UNCL homologues are present in two yeast and a plant species, none of which express nicotinic receptors and it is also found in tissues that lack nicotinic receptors.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.