Family

Glycosyltransferase, ALG3 (IPR007873)

Short name: Glycosyltransferase_ALG3

Family relationships

None.

Description

The formation of N-glycosidic linkages of glycoproteins involves the ordered assembly of the common Glc3Man9GlcNAc2 core-oligosaccharide on the lipid carrier dolichyl pyrophosphate. Whereas early mannosylation steps occur on the cytoplasmic side of the endoplasmic reticulum with GDP-Man as donor, the final reactions from Man5GlcNAc2-PP-Dol to Man9GlcNAc2-PP-Dol on the lumenal side use Dol-P-Man [PMID: 11308030]. The ALG3 gene encodes the Dol-P-Man:Man5GlcNAc2-PP-Dol mannosyltransferase.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016758 transferase activity, transferring hexosyl groups

Cellular Component

GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER