Family

Ameloblastin precursor (IPR007798)

Short name: Amelin

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This family consists of mammalian Ameloblastin precursor (Amelin) proteins. Matrix proteins of tooth enamel consist mainly of amelogenin but also of non-amelogenin proteins, which, although their volumetric percentage is low, have an important role in enamel mineralization. One of the non-amelogenin proteins is ameloblastin, also known as amelin and sheathlin. Ameloblastin (AMBN) is one of the enamel sheath proteins which is thought to have a role in determining the prismatic structure of growing enamel crystals [PMID: 11867231].

GO terms

Biological Process

GO:0042475 odontogenesis of dentin-containing tooth

Molecular Function

GO:0030345 structural constituent of tooth enamel

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER
SMART