Family

Ameloblastin precursor (IPR007798)

Short name: Amelin

Family relationships

None.

Description

This family consists of mammalian Ameloblastin precursor (Amelin) proteins. Matrix proteins of tooth enamel consist mainly of amelogenin but also of non-amelogenin proteins, which, although their volumetric percentage is low, have an important role in enamel mineralization. One of the non-amelogenin proteins is ameloblastin, also known as amelin and sheathlin. Ameloblastin (AMBN) is one of the enamel sheath proteins which is thought to have a role in determining the prismatic structure of growing enamel crystals [PMID: 11867231].

GO terms

Biological Process

GO:0042475 odontogenesis of dentin-containing tooth

Molecular Function

GO:0030345 structural constituent of tooth enamel

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
SMART
PANTHER