Herpesvirus major outer envelope glycoprotein (IPR007796)

Short name: Herpes_BLLF1

Overlapping homologous superfamilies


Family relationships



This family consists of the viral late glycoprotein BLLF1, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo. The binding of the viral major glycoprotein BLLF1 to the CD21 cellular receptor is thought to play an essential role during infection of B lymphocytes by the Epstein-Barr virus (strain GD1) (HHV-4) (Human herpesvirus 4) [PMID: 11024143].

GO terms

Biological Process

GO:0019058 viral life cycle

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0019031 viral envelope

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.