Vitamin K-dependent gamma-carboxylase (IPR007782)

Short name: VKG_COase

Family relationships



Using reduced vitamin K, oxygen, and carbon dioxide, gamma-glutamyl carboxylase post-translationally modifies certain glutamates by adding carbon dioxide to the gamma position of those amino acids. In vertebrates, the modification of glutamate residues of target proteins is facilitated by an interaction between a propeptide present on target proteins and the gamma-glutamyl carboxylase [PMID: 10748045].

GO terms

Biological Process

GO:0017187 peptidyl-glutamic acid carboxylation

Molecular Function

GO:0008488 gamma-glutamyl carboxylase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.