Toxin-antitoxin system, RelE/ParE toxin family (IPR007712)

Short name: RelE/ParE_toxin

Overlapping homologous superfamilies

Family relationships


The RelE/ParE family encompasses several toxin components of toxin-antitoxin modules. RelE is a sequence-specific, ribosome-dependent mRNA endoribonuclease which inhibits translation during amino acid starvation [PMID: 15718296]. ParE is involved in plasmid partition. ParE acts by inhibiting DNA gyrase, converting supercoiled plasmid DNA into a singly cleaved linear form in an ATP-dependent fashion [PMID: 8133518, PMID: 12010492].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.