Family

Mannosyltransferase, DXD (IPR007704)

Short name: Mannosyltransferase_DXD

Family relationships

None.

Description

PIG-M has a DXD motif. The DXD motif is found in many glycosyltransferases that utilise nucleotide sugars. It is thought that the motif is involved in the binding of a manganese ion that is required for association of the enzymes with nucleotide sugar substrates [PMID: 11226175].

GO terms

Biological Process

GO:0006506 GPI anchor biosynthetic process

Molecular Function

GO:0016758 transferase activity, transferring hexosyl groups

Cellular Component

GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER