Domain

SGS (IPR007699)

Short name: SGS

Domain relationships

None.

Description

This domain was thought to be unique to the SGT1-like proteins, but is also found in calcyclin binding proteins. Sgt1p is a highly conserved eukaryotic protein that is required for both SCF (Skp1p/Cdc53p-Cullin-F-box)-mediated ubiquitination and kinetochore function in yeast and also plays a role in the cAMP pathway. Calcyclin (S100A6) is a member of the S100A family of calcium binding proteins and appears to play a role in cell proliferation [PMID: 12577318].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PROSITE profiles