Family

Ran-interacting Mog1 protein (IPR007681)

Short name: Mog1

Overlapping homologous superfamilies

Family relationships

None.

Description

Segregation of nuclear and cytoplasmic processes facilitates regulation of many eukaryotic cellular functions such as gene expression and cell cycle progression. Trafficking through the nuclear pore requires a number of highly conserved soluble factors that escort macromolecular substrates into and out of the nucleus. The Mog1 protein has been shown to interact with RanGTP, which stimulates guanine nucleotide release, suggesting Mog1 regulates the nuclear transport functions of Ran [PMID: 11733047]. The human homologue of Mog1 is thought to be alternatively spliced.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
CDD
PANTHER