Family

Gasdermin (IPR007677)

Short name: Gasdermin

Family relationships

None.

Description

The precise function of this protein is unknown. However, it is thought that this entry represents the Gasdermin family which plays a role as secretory or metabolic product involved in secretory pathway and includes Gasdermin, Non-syndromic hearing impairment protein 5 (DFNA5)and Pejvakin.

It may also play a role in achieving and maintaining the final differentiation state of epithelial cells [PMID: 15010812, PMID: 18038310]. A deletion/insertion mutation is associated with an autosomal dominant non-syndromic hearing impairment form [PMID: 9771715].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER