Family

Microvirus lysis protein (E) (IPR007605)

Short name: Micrvir_lysisE

Family relationships

None.

Description

E protein causes host cell lysis by inhibiting MraY, a peptidoglycan biosynthesis enzyme. This leads to cell wall failure at septation [PMID: 12100551]. The N-terminal transmembrane region matches the signal peptide model and must be omitted from the family.

GO terms

Biological Process

GO:0019054 modulation by virus of host process

Molecular Function

GO:0004857 enzyme inhibitor activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
ProDom