Family

(5-formylfuran-3-yl)methyl phosphate synthase (IPR007565)

Short name: 4-HFC-P_synthase

Family relationships

None.

Description

This entry represents the (5-formylfuran-3-yl)methyl phosphate synthase (also known as 4-HFC-P synthase or MfnB), which has a classical TIM-barrel structure whose biological unit is a homohexamer. It is involved in the production of methanofuran. MfnB from Methanocaldococcus jannaschii catalyzed at least 10 separate chemical reactions in converting two molecules of glyceraldehyde-3-P (GA-3-P) to 4-(hydroxymethyl)-2-furancarboxaldehyde-P (4-HFC-P), the first discrete intermediate in the biosynthetic pathway to the furan moiety of the coenzyme methanofuran [PMID: 25905665].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
HAMAP
PIRSF