SWIRM domain (IPR007526)

Short name: SWIRM

Overlapping homologous superfamilies

Domain relationships



The SWIRM domain is a small alpha-helical domain of about 85 amino acid residues found in eukaryotic chromosomal proteins. It is named after the proteins SWI3, RSC8 and MOIRA in which it was first recognised. This domain is predicted to mediate protein-protein interactions in the assembly of chromatin-protein complexes [PMID: 12186646].

The SWIRM domain can be linked to different domains, such as the ZZ-type zinc finger (IPR000433), the Myb DNA-binding domain (IPR001005), the HORMA domain (IPR003511), the amino-oxidase domain, the chromo domain (IPR000953), and the JAB1/PAD1 domain.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005515 protein binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE profiles