Bacterial virulence protein VirB8 (IPR007430)

Short name: VirB8

Overlapping homologous superfamilies

Domain relationships


VirB8 is a bacterial virulence protein with cytoplasmic, transmembrane, and periplasmic regions. It is thought that it is a primary constituent of a DNA transporter. The periplasmic region interacts with VirB9, VirB10, and itself [PMID: 11371528]. It is required for stabilisation of VirB3 (an inner membrane protein) [PMID: 20348257]. This family also includes the conjugal transfer protein family TrbF, a family of proteins known to be involved in conjugal transfer. The TrbF protein is thought to compose part of the pilus required for transfer [PMID: 11846762].

This entry represent a protein fold, which is similar to that of the NTF2-like family [PMID: 16481621].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.