Prokaryotic chromosome segregation/condensation protein MukE (IPR007385)

Short name: Scp_MukE

Overlapping homologous superfamilies


Family relationships



This family contains MukE, which are proteins involved in the segregation and condensation of prokaryotic chromosomes. MukE along with MukF (IPR005582) interact with MukB (IPR007406) in vivo forming a complex, which is required for chromosome condensation and segregation in Escherichia coli [PMID: 10545099]. The Muk complex appears to be similar to the SMC-ScpA-ScpB complex in other prokaryotes where MukB is the homologue of SMC [PMID: 12065423]. ScpA (IPR003768) and ScpB (IPR005234) have little sequence similarity to MukE or MukF, though they are predicted to be structurally similar, being predominantly alpha-helical with coiled coil regions.

GO terms

Biological Process

GO:0030261 chromosome condensation
GO:0007059 chromosome segregation

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005737 cytoplasm

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.