Domain

Circularly permuted ATPgrasp domain (IPR007302)

Short name: CP_ATPgrasp

Domain relationships

None.

Description

This ATP-grasp domain is present both as catalytically active and inactive versions. Contextual analysis suggests that it functions in a distinct peptide synthesis/modification system that additionally contains a transglutaminase, an NTN-hydrolase, the Alpha-E domain, and a transglutaminase fused N-terminal to a circularly permuted COOH-NH2 ligase. The inactive forms are often fused N-terminal to the Alpha-E domain [PMID: 20023723].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam