CidB/LrgB family (IPR007300)

Short name: CidB/LrgB

Family relationships


The two products of the lrgAB operon are potential membrane proteins. LrgA and LrgB are antiholin-like proteins thought to control murein hydrolase activity and penicillin tolerance [PMID: 10714982] and to inhibit the holin-like proteins from the cidAB operon, CidA and CidB [PMID: 12670989]. The regulatory processes by these proteins is still largely unknown.

This family represents LrgB and CidB.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.